A jacketed glass reactor is a type of chemical reactor made from glass that has an outer jacket surrounding the main reaction vessel. The jacket allows a heating or cooling fluid to circulate around the reaction vessel, providing precise temperature control of the contents inside.
Main features of a jacketed glass reactor:
- The inner reaction vessel is made of glass, such as borosilicate glass, allowing visibility of the reaction. Glass is inert to many chemicals.
- The outer jacket surrounds the inner vessel, with space in between. It is often made of glass or metal.
- The space between the inner vessel and outer jacket forms a closed loop that has ports to allow heating/cooling fluid in and out.
- Heating or cooling fluid (like water, oil, steam, refrigerants) can be pumped through the jacket to control the temperature of the reactor contents.
- The jacket provides even, precise temperature control unlike external heating with a hot plate or oil bath.
- Useful for many chemical reactions that require temperature control, including distillations, extractions, crystallizations, and synthetic chemistry.
- Jacketed reactors often have additional ports for adding/removing contents, as well as measurement probes.
- Available in a wide range of sizes from laboratory scale to industrial production scale.

Advantages of using a jacketed glass reactor
- Precise temperature control: The jacketed design allows for precise temperature control, which is crucial for many chemical reactions. The heating or cooling fluid can be circulated through the jacket to control the temperature of the contents inside the vessel.
- Faster heat transfer: The jacketed design allows for faster heat transfer between the heating or cooling fluid and the contents inside the vessel, which can speed up the reaction and increase productivity.
- Visual observation: The glass material of the reactor allows for visual observation of the reaction, which is important for monitoring the progress of the reaction and determining when it is complete.
- Corrosion resistance: The glass material of the reactor is resistant to corrosion from the chemicals used in the reaction, which can extend the life of the reactor and reduce maintenance costs.
- Easy cleaning: The glass material of the reactor is easy to clean and sterilize, which is important for maintaining the purity of the reaction.
- Versatility: Jacketed glass reactors are available in various sizes and configurations, making them suitable for a wide range of applications in chemistry, pharmaceuticals, and other fields.
In summary, the advantages of using a jacketed glass reactor include precise temperature control, faster heat transfer, visual observation, corrosion resistance, easy cleaning, and versatility. These advantages make jacketed glass reactors ideal for a wide range of chemical and pharmaceutical applications.